The San Diego Padres hit the road to face the Houston Astros in the first of a three-game series at Daikin Park. Read our preview of the Diego Padres VS Houston Astros.
The Padres are red-hot at 15-4, while the Astros are still searching for consistency at 8-10. Matchplug has the odds, preview, and prediction for this exciting Friday night matchup.
The game is scheduled for 00:10 AM on Saturday.
Betting Preview for San Diego Padres VS Houston Astros
- Venue: Daikin Park, Houston
- Date: Sunday, April 20th, 2025
- Time: 00:10 AM
- Teams: San Diego Padres VS Houston Astros
- Odds provided by 1XBet
Betting On The San Diego Padres
- 1XBet Spread: -1.5
- 1XBet Moneyline: 1.848
- 1XBet Over/Under: Over 7.5
San Diego enters this series on fire, with the best record in the league and a dominant offense. They lead the MLB with a .274 team batting average and their pitching has also been excellent, ranking near the top with a 2.56 ERA and holding opponents to a .193 average.
Kyle Hart gets the start for the Padres. He’s 2-0 through three starts with a 5.40 ERA, but his solid 1.11 WHIP suggests better control than the ERA shows. With San Diego’s deep lineup backing him, the Padres are in a strong position to take Game One.
Betting On The Houston Astros
- 1XBet Spread: +1.5
- 1XBet Moneyline: 2.02
- 1XBet Over/Under: Under 7.5
Houston has yet to build momentum this season. Through 18 games, they’ve never won back-to-back and are hitting just .216 as a team. The pitching has carried them with a 3.73 ERA and 181 strikeouts.
Ryan Gusto will open the game for Houston, likely as a short-inning starter. He hasn’t gone past four innings in any of his five appearances, so this looks like a bullpen game. Houston’s bullpen ERA of 2.94 is a bright spot, especially at home where they’ve been better.
MatchPlug Prediction For San Diego Padres VS Houston Astros
Houston is due for a bounce-back, but it’s hard to bet against a Padres team firing on all cylinders. With both strong pitching and the league’s top batting average, San Diego has the edge. The Astros’ bullpen might keep it close, but San Diego’s offense should eventually break through.
Final Prediction: Padres Over/Under
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