Inter Milan host Sassuolo at the Stadio Giuseppe Meazza on Sunday evening in Serie A, as the Nerazzurri look to bounce back from their dramatic defeat to Juventus. Christian Chivu’s side have already dropped six points this season and cannot afford another slip-up in the title race. MatchPlug brings you the odds and analysis for Inter vs Sassuolo.
The match is scheduled for Sunday, September 21st, 2025, at 8:45 PM CET.
Here’s everything you need to know before making your picks.
Betting Preview for Inter Milan vs Sassuolo
- Venue: Stadio Giuseppe Meazza
- Date: Sunday, September 21st, 2025
- Time: 20:45 CET
- Teams: Inter Milan vs Sassuolo
- Odds provided by 1XBet
Betting On Inter Milan
1XBet Spread: -1.5
1XBet Moneyline: 1.40
1XBet Over/Under: Over 2.5
Inter fell 4-3 to Juventus last weekend but showed plenty of attacking firepower despite the loss. The Nerazzurri remain strong favorites at home, where they’ve traditionally dominated fixtures like this. Lautaro Martínez is racing to be fit, while Matteo Darmian is sidelined, but Chivu’s squad still boasts plenty of depth in the forward areas.
With their Scudetto aspirations on the line, Inter will be expected to take the initiative from the start, particularly against a Sassuolo side that struggles away from home.
Betting On Sassuolo
1XBet Spread: +1.5
1XBet Moneyline: 7.00
1XBet Over/Under: Under 2.5
Sassuolo enter this game on a high after upsetting Lazio last weekend, thanks to a winner from summer arrival Alieu Fadera. However, their poor away form has been a recurring issue, with defensive lapses often costing them against stronger sides.
While they are capable of finding the net, especially on the counter, their record at San Siro does not inspire confidence.
MatchPlug Prediction For Inter Milan vs Sassuolo
Inter have the attacking quality and the home advantage to make a statement here, especially after the disappointment in Turin. Sassuolo can threaten on the break, but their defensive frailties should be exposed by the Nerazzurri’s frontline.
Final Prediction: Inter Milan to win & Over 2.5 Goals
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