NFL Predictions    Tennessee Titans vs. Buffalo Bills   Over/Under: 48.5  Odds: Titans +9.5, Bills –9.5  Time: 7:15 PM ET    NFL Predictions We have some more Week 2 action in the NFL with the Tennessee Titans taking on the Buffalo Bills. Tennesse had an awful opening game, losing to the New York Giants despite being heavily favored. As for the Bills, they dominated the reigning Super Bowl champion Los Angeles Rams.   The Titans had a relatively simple day in the box score against the Giants. Ryan Tannehill threw for 266 yards and two touchdowns without an interception while Derrick Henry took 21 carries for 82 yards. The problem was that none of it stood out. They slowly pushed the ball down field throughout the game but weren’t making big plays and taking momentum. This resulted in them getting shutout in the fourth quarter and only scoring 20 points total. Now, their defense did rack up five sacks on the day with two forced fumbles and an interception. That was the real takeaway from them. Though it could honestly be seen as more concerning given the fact that they rarely converted on them.   Meanwhile, the Bills just lit up the leagues most stacked defense. The Rams have Jalen Ramsey, Bobby Wagner, Aaron Donald and so many others and yet Buffalo made it look easy last week. Josh Allen threw for 297 yards, three touchdowns and two interceptions while only missing four throws. One of those interceptions wasn’t even his fault as the receiver dropped the pass. Allen also had 10 rushes for 56 yards and another touchdown. Everywhere you looked, these guys came out and performed. On defense, Buffalo was flying all over the field with three interceptions and seven sacks in total. If this team plays consistently all year long, I wouldn’t want to be the guys going against them.    NFL Picks Today Shockingly, the Titans have been playing well against Buffalo in the last two years. These two teams have matched up five times over the past five years. Tennessee won the first one, then the Bills rattled off two straight, and now the Titans have won two straight against them.   It’s not hard to see why Buffalo is the favored team in this game after what we’ve seen from these groups in Week 1. I have to be rolling with the Bills and the spread here given the offensive talent and the way the defensive line got after Matthew Stafford and the Rams offense. Tennessee does of course have Derrick Henry to shoulder the load, but we all know that. I believe Buffalo will lock down Henry and force Tannehill to win the game with his arm, and I simply don’t see him outdueling Josh Allen and Stefon Diggs with AJ Brown now on the Philadelphia Eagles.   As for the total, it’s set at 48.5. I would roll with the over in this matchup. Both of their last two games have hit the over and with how hot Buffalo is offensively at the moment, points will be scored often. In 2021, the final hit 65 points. The previous matchup in 2020 saw the total hit 58. This seems to be one of the safer bets to make.   Final Pick: Bills –9.5  Over/Under Choice: Over 48.5  If you’re looking for more content, click here!