Wednesday’s MLB action rolls into Oriole Park at Camden Yards as the St. Louis Cardinals and Baltimore Orioles wrap up their three-game interleague series. Read our preview for the Cardinals vs Orioles.  The Orioles took the opener and aim to win the set in front of their home crowd. Read on for our prediction and betting insights. Betting Preview For Cardinals vs Orioles Betting On St. Louis Cardinals The Cardinals saw their three-game winning streak snapped with a quiet night at the plate on Monday, managing just four hits and committing two key defensive errors. St. Louis is still riding a strong May and remains in contention in the NL Central, just behind the Cubs. Miles Mikolas gets the nod, bringing a 4-2 record and 3.51 ERA into his 11th start of the season. He’s been in great form recently, giving up just two earned runs in his last 17.1 innings. While the Cardinals’ offense has been top-10 overall, it has slumped hard against left-handed pitching, hitting just .556 OPS over the past 10 days. Betting On Baltimore Orioles The Orioles may be having a disappointing season overall, but they’ve picked up momentum with a three-game win streak. A key swing by Dylan Carlson powered them past St. Louis in the opener, and they’ll aim to continue riding that wave. Cade Povich starts for Baltimore, carrying a 1-3 record and 4.86 ERA. While his season stats are mediocre, he’s looked sharper lately, allowing only three earned runs over his last 10.2 innings. The Cardinals have never faced Povich, and Baltimore’s offense has performed well against righties recently, logging a .734 OPS over the last 10 days. MatchPlug Prediction For Cardinals vs Orioles The Orioles have the edge here thanks to their current offensive form against right-handers and the Cardinals’ struggles against southpaws. Cade Povich has shown signs of improvement and faces a St. Louis lineup that hasn’t figured out lefties lately. With Baltimore showing fight and home-field advantage, we’re backing the O’s to win the rubber match. Final Prediction: Baltimore Orioles Moneyline (-115)

The San Francisco Giants aim to avoid a sweep as they face the surging Minnesota Twins on Sunday afternoon in the series finale at Target Field. Read our preview for the Giants vs Twins.Minnesota has won seven straight games, including the first two of this series, while San Francisco looks to rebound behind one of their promising young arms. First pitch is scheduled for Sunday at 2:10 PM EST. Check out our Giants vs Twins prediction below, and don’t forget to follow MatchPlug for more Free MLB Picks and betting tips. Betting Preview For Giants vs Twins Odds provided by 1XBet Betting On San Francisco Giants San Francisco enters the game with a strong 22-14 record and a notable 22-7 mark against right-handed starters, making them a live underdog here. Their offense has gone cold this series, with just two total runs in the first two games, but they remain dangerous, especially with righty bats like Matt Chapman and Wilmer Flores looking to break out. Rookie starter Landen Roupp gets the nod after an impressive showing against the Angels where he struck out nine over seven innings. His curveball has been his out pitch, and with a developing cutter and changeup, he has the tools to compete with a confident Twins lineup. Betting On Minnesota Twins Minnesota is red-hot with seven consecutive wins and a dominant home record of 14-6. Their pitching has led the way during this stretch, allowing just two runs combined in the first two games against San Francisco. Pablo López starts for the Twins and has been excellent this year, posting a 3–2 record and a sharp 2.18 ERA. He went seven innings of one-run ball in his last outing against Baltimore and will be tasked with keeping the Giants’ righty-heavy lineup in check. MatchPlug Prediction For Giants VS Twins This is a classic value spot. The Twins are rolling, but the Giants have played close games all series and thrive against right-handed pitching. Landen Roupp is ascending, and with the Giants catching +120 odds, the risk-reward angle favors backing San Francisco to snap Minnesota’s streak. Final Prediction: San Francisco Giants Moneyline

The New York Mets host the Chicago Cubs on Sunday afternoon to wrap up their three-game series at Citi Field. Read our preview for the Cubs vs Mets. Both teams are over .500, but the Mets continue to dominate at home while the Cubs are aiming to salvage the finale after dropping the opener. First pitch is scheduled for 1:40 PM EST. Read on for our Cubs vs Mets prediction and check MatchPlug daily for more Free MLB Picks and betting previews. Betting Preview For Cubs vs Mets Odds provided by 1XBet Betting On Chicago Cubs The Cubs send veteran lefty Matt Boyd to the hill, who has been effective overall with a 2.75 ERA and a 3-2 record. He tossed six strong innings in his last start, allowing just two runs against San Francisco. However, Boyd has struggled slightly on the road (0-2) and in his lone start vs. the Mets, he gave up three runs in five innings. Chicago remains in first place in their division but enters Sunday’s contest having lost four of their last five games. The offense has shown flashes, but the pitching staff allowed 20 runs in a recent series against the Giants and hasn’t been consistent lately. Betting On New York Mets Griffin Canning has emerged as a stabilizing force in the Mets rotation, boasting a 5-1 record with a 2.50 ERA. He’s allowed one or zero earned runs in four of his last five starts and has helped New York win each of his past six outings. The Mets are 14-3 at Citi Field this season and come into this game with wins in three of their last four contests. They bounced back from a series loss to St. Louis by taking two of three from Arizona on the road and continue to play with confidence behind strong pitching. MatchPlug Prediction For Cubs vs Mets The Mets are clicking at home and have a decisive edge on the mound with Canning in top form. Boyd has been steady, but his road performances raise concerns. With the Mets backing their hottest pitcher and sporting a 14-3 home record, we’ll ride the momentum. Final Prediction: New York Mets ML