Napoli recovered from their 2-0 loss at Liverpool to beat Atalanta 2-1 to continue their match towards winning the Serie A table.
The loss to Liverpool remains their only defeat in all competitions this season and Luciano Spaletti will expect his team to get back to form against Empoli.
Napoli are six points clear at the top of the league table ahead of this match and they will be desperate to ensure they can keep their nine-game winning run intact after this fixture.
Victor Osimhen has recovered from injury to lead their attack with 8 goals in the league alone this term, but can Empoli stop the in-form Nigerian?
Empoli is having an inconsistent season and they head to Naples for this fixture with just two wins from their last five matches.
They impressively beat Napoli home and away when both clubs met in the league last season, this should serve as extra motivation for the league leaders to get the job done.
The best bet prediction for this game is over 1.5 goals. For similar predictions, click here.