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MLB Prediction Today: San Diego Padres vs Cincinnati Reds Prediction

The San Diego Padres face off against the Cincinnati Reds in the second matchup of their three-game National League series on Saturday.

Read our full preview for the San Diego Padres vs Cincinnati Reds game.Both teams are pushing for playoff spots, but it’s the Reds who come in hot after nearly throwing a no-hitter in Friday’s dominant 8-1 win.

The game is scheduled for 9:10 PM WAT at Great American Ball Park.Matchplug is your best plug for up-to-date betting picks and analysis.

With elite pitching from Cincinnati and San Diego’s lineup going cold, the Reds look primed to keep rolling at home.

Betting Preview for San Diego Padres vs Cincinnati Reds

  • Venue: Great American Ball Park, Cincinnati
  • Date: Saturday, June 29th, 2025
  • Time: 9:10 PM WAT (4:10 PM EST)
  • Teams: San Diego Padres vs Cincinnati Reds
  • Odds as provided by 1XBet

Betting on the San Diego Padres

  • 1XBet Spread: +1.5
  • 1XBet Moneyline: +130
  • 1XBet Over/Under: Under

The Padres were completely shut down on Friday, managing just one hit in the 8-1 loss. They’ve now dropped three of their last four and are only hitting .226 against NL Central teams.Randy Vasquez will get the start with a 3.60 ERA through 16 games this season.

He allowed two runs in seven innings in his last outing and holds a 4.14 ERA on the road. While Vasquez has been decent, San Diego’s offense hasn’t supported him, ranking in the bottom 10 in runs and home runs.

Betting on the Cincinnati Reds

  • 1XBet Spread: -1.5
  • 1XBet Moneyline: -150
  • 1XBet Over/Under: Over

The Reds have been surging, winning eight of their last 12. Nick Martinez flirted with a no-hitter on Friday, and Spencer Steer crushed three home runs in one of their best performances of the season.On Saturday, they’ll start Andrew Abbott, who’s been elite.

The left-hander boasts a 7-1 record with a 1.79 ERA, including a 2.17 ERA at home. Cincinnati is 5-2 when Abbott pitches at Great American Ball Park, and their .259 average against NL West teams bodes well against the Padres’ cold bats.

MatchPlug Prediction for San Diego Padres vs Cincinnati Reds

The Reds have the hotter offense and a red-hot starter in Andrew Abbott, while the Padres are reeling from Friday’s near no-hitter. San Diego has struggled all year against NL Central teams, and Saturday likely brings more of the same.

Our prediction for this one is a solid home win for Cincinnati behind another strong showing from Abbott.

Final Prediction: Cincinnati Reds -1.5

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