Ajax trashed Dortmund 4-0 when these clubs met in the reverse of this fixture and this gives the Germans the chance to avenge that defeat.
Ajax has reemerged and now looks likely to match their feat when they reached the semi-final of the Champions League in 2019.
The Dutchmen are making incredible progress and are leading their Champions League group ahead of this game.
Dortmund is second on the table, but they are closely followed by Sporting CP and they know they need a result from this game.
Ajax has been almost unstoppable, but they were beaten by Utrecht at the start of last month.
They have recovered well, but they head into this fixture after a goalless draw at Heracles.
This game would be a huge clash between two of Europe’s most exciting clubs to watch.
However, the Germans would feel that they need to win the game even more than their visitors.