The San Francisco Giants visit the LA Angels for their only three-game series this season, starting Friday night. Read our preview for the San Francisco Giants vs LA Angels game. Both teams are coming off Thursday losses and are looking to bounce back in Game 1. Matchplug has the odds, preview, and prediction for this interleague matchup.
The game is scheduled for 9:38 PM ET on Friday.
Betting Preview for San Francisco Giants VS LA Angels
- Venue: Angel Stadium, Anaheim
- Date: Saturday, April 20th, 2025
- Time: 9:38 PM ET
- Teams: San Francisco Giants VS LA Angels
- Odds provided by 1XBet
Betting On The San Francisco Giants
- 1XBet Spread: -1.5
- 1XBet Moneyline: 1.70
- 1XBet Over/Under: Over 8.5
The Giants are 13-6 and have been one of the best offensive teams in the league, ranking third in total runs. Their pitching has also been solid, with a team ERA of 3.63, 9th in the MLB. Despite a shaky last outing from their starter, San Francisco will be confident heading into this one.
Betting On The LA Angels
- 1XBet Spread: +1.5
- 1XBet Moneyline: 2.171
- 1XBet Over/Under: Under 8.5
The Angels have lost four straight and are struggling after a strong start to the season. They dropped their last two series and now sit third in the AL West. With both starters in poor form and their offense cooling off, they’ll need a strong showing at home to get back on track.
MatchPlug Prediction For San Fransisco Giants VS Angels
The Giants have been better on both sides of the ball and should take advantage of an Angels team that’s trending downward. Look for San Francisco’s bats to make the difference.
Final Prediction: Giants Over/Under
