Nigeria visits Sao Tome and Principe after their 2-1 home win against Sierra Lone and will be keen to avoid an upset in this fixture.
That win was a good start for their new manager, Jose Peseiro, in competitive games after his side lost to Ecuador and Mexico in previous friendly matches.
Nigeria missed out on the World Cup by losing their playoff game to Ghana, but they know they cannot fail to qualify for the next Cup of Nations.
Sao Tome is one of the minnows of African football and this match is a fixture that they are very likely to lose unless they cause a major upset.
The host has just a win from their last five competitive matches and three of them have ended in losses for them.
Nigeria, on the other hand, has lost none of their last three matches against African opponents and they will be keen to ensure they get another win from this fixture.
This is the first time both countries are meeting each other and the Super Eagles will want to make it count.